if it's a 2 door then yes...

manual would be better as well as they use the same box as the 350Z... HOWEVER... if she gets the auto it's like an 8 speed or something and when they screw up all hell goes loose it's hard to find someone that will rebuild it with the knowledge that requires to bring it back to tip top shape... or then you would have to find another box and that could be real easy or really hard...

don't take the risk and buy something else (unless it's manual with brembo's)

IS200's are good... and the C series Mercs are going for good prices too ('03-'05) models

as well as E46 BMW's you could even pick up an E46 320Ci for like mid-20's but then you're looking at 100,000km's +/- i'm not sure if that's an issue for her

keep in mind when you're considering luxury (dependent on what you buy of course) maintanence can go through the roof!

all the best to your sister and what she decides, keep us informed hey!

EDIT: the cars i've listed are going for around the same price as an '03 V35 Coupe... Sedan is cheaper of course