I use usb loader gx with a 320gb WBFS formatted hdd (games put on with WBFS manager), been my favourite setup.

edit: For above, I know usb loader gx has a +002 error fix thing/patch where you just turn it on for specific games if it occurs. Maybe try a new loader.

Check out gbatemp website/forums, has EVERYTHING you need and is where all the latest loaders etc. are updated. Just have to sort through all the information.